These intermediate results are now combined to \begin{equation} \left[ \frac{\partial}{\partial x}\left( q(x) \frac{\partial u}{\partial x}\right)\right]^n_i \approx \frac{1}{\Delta x^2} \left( q_{i+\half} \left({u^n_{i+1} - u^n_{i}}\right) - q_{i-\half} \left({u^n_{i} - u^n_{i-1}}\right)\right) \tag{24} \end{equation}
In operator notation: \begin{equation} \left[ \frac{\partial}{\partial x}\left( q(x) \frac{\partial u}{\partial x}\right)\right]^n_i \approx [D_xq D_x u]^n_i \tag{25} \end{equation}
Many are tempted to use the chain rule on the term \frac{\partial}{\partial x}\left( q(x) \frac{\partial u}{\partial x}\right) , but this is not a good idea!